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Volume-21 (2022);
No. 1 (January-March)
Published on April 30, 2022
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2022;1:1
Original Article |
Waghela D, Nagar S, Ravi RP.
Malnutrition among Under Five Children in Peri-Tribal areas: A study on Prevalence and Factors associated in Vadodara District of Gujarat State in India. |
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Abstract: Background: Malnutrition among under-five children is a foremost public health problem across India. United Nation estimates that 6.3 million under age-five mortality were occurred in India, of which 45% died due to malnutrition. The objective of the study was to find out the prevalence and factor associated with malnutrition in term of underweight, stunning, and wasting in children under five years of age in peri-tribal areas. Methods: Cross sectional study was conducted at the Anganwadi centres in 6 villages under the Rural Health Training Centre. Out of nine Anganwadi centres, five were selected using systematic random sampling method. Total of 370 children aged below five years were selected. Results: Among the 370 children aged 0-5 years, (29.1%) children were normally nourished, (70.79%) children were malnourished and had one or more form of malnutrition. Only stunting was present in (19.5%) children and only wasting was present in (8.9%) children. Children (5.94%) was suffering from underweight and stunting both. Stunting and wasting both was present in (22.16%) children and wasting and underweight both was present in (10.5%) children. respectively, (1%) Children were suffering from underweight, stunting and wasting. All three indices (Underweight, Stunting & Wasting) of under nutrition were found to be higher in low-birth-weight children. Conclusion: Mother's educational qualification is strongly associated with nutritional status of their children. This might be due to better health care practices in terms of proper exclusive breast feeding, in-time complementary feeding and quality and quantity of complementary feeding among literate mothers as compared to illiterate mothers.
Key words: Malnutrition, Underweight, Stunting, Wasting, Birth Weight, Health Education. |
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2022;1:2
Original Article |
Lepcha M, Mondal N.
Association of Socio-economic Factors with Fertility and Mortality among Lepchas of North Sikkim, India. |
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Abstract: Background: Fertility is the physiological ability to have children or to produce offspring whereas; mortality means death of any member of the population. In demographic study which is basically the study of any population, fertility rate and mortality rate are considered to be important determinants alongside migration which is the settlement pattern of people from one place of origin to another. Objectives: The objective of the present
cross-sectional investigation is to analyze the association of socio- economic factors with fertility and mortality among the Lepcha
tribal population of North Sikkim, India. Methods: For the present investigation, data was collected from 110 married women aged 18- 60 years from different villages of Dzongu, North Sikkim. Data on fertility and mortality information were obtained from each married woman along with their spouses. Results: The mean age at marriage and age at first child birth were
observed to be higher and the difference was statistically significant (p<0.05). Live births and surviving children with respect to education of women is statistically significant, with values for live births (F= 5.088, p<0.01) and surviving children (F=4.040, p<0.05). The number of mothers with infant mortality was observed to be higher in the low-income group (1.29±0.18). Results indicated that 81% from the low-income group have not opted for family planning, but 44.4 % have reported the use of contraceptive methods. Conclusion:
The study indicates that socio-economic, socio-cultural and
biological factors have an impact on fertility and mortality and has
led to its decrease among the Lepcha tribal population of North Sikkim.
Key words: Fertility, Mortality, Demography, Lepcha, women education |
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2022;1:3
Original Article |
Dharmaraj A, Chinnaiyan S, Ghimire A, Barik RK, Tiwari AK.
Effect of Household Cooking Fuel and Breastfeeding on Infant Growth: Findings from the National Family Health Survey-4, India. |
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Abstract: Objective: Malnutrition is a critical public health concern in India. We aimed to understand the prevalence of stunting and its association between cooking fuel type and breastfeeding among Indian infants (≤ 6 months of age). Methods: This study used information from a National Family Health Survey-4 (NFHS) conducted between 2015 and 2016. From all eligible infants, information on socio-demographic and clinical characteristics was obtained. Univariate and multivariable binary logistic regression was performed to examine the factors associated with stunted children. Results: Of the 15,120 infants, the median (Inter Quartile Range) age was 4 (2-5) months with a female/male ratio of 1:1.06. The prevalence of polluting fuel use and stunting was 68.10% and 20.13% respectively. Stunting among polluting fuel and clean fuel was 22.17% and 15.78%. Stunting among exclusive breastfed and not exclusive breastfed was 20.62% and 19.53%. In adjusted analysis, households using clean fuel (Adjusted Odds Ratio 0.75; 95% Confidence Interval, 0.66-0.86) had lower odds of infants being stunted compared to polluting fuel. A infant currently being breastfed (aOR 0.76; 95% CI, 0.62-0.93) had lower odds of being stunted than infants currently not being breastfed. Conclusion: The present study indicates that polluting cooking fuel and not being breastfed was associated with an increased risk of infant being stunted. A community-based randomized control trial was required to study child and maternal health risks on polluting cooking fuel. Furthermore, the study highlights the urgent need to raise awareness on the importance of exclusive breastfeeding practices.
Key words: Biomass, breastfeeding, infants, cooking fuel, particulate matter, stunting |
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2022;1:4
Original Article |
Bhattacharya A, Mehrotra S, Bhola P.
Challenges to Mental Wellbeing, Perceived Resources, and Felt Needs During COVID-19 Among College Youth in India. |
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Abstract: COVID-19 has significantly impacted the mental health and well-being of college youth across the world. An online survey using checklists and open-ended questions was shared across various institutions in India to capture information about challenges faced, internal and external resources utilized to deal with the stress, existing support systems and suggestions for additional support for maintaining well-being by college youth. Thematic analysis was conducted to understand the emergent themes. Findings suggested that the most challenging aspect of the pandemic was worry about academics, career, and health of loved ones. The most useful self-management strategies to deal with stress were pursuing hobbies, learning new things, spending time with family, sharing concerns and positive self-talks. The students suggested more robust academic as well as mental health support mechanisms at the university level. At the community level students highlighted the need for community based mental health programs and more support from families. This is one of the very first exploratory studies on the potential mental health impact of the pandemic on Indian university students.
Key words: COVID-19, youth mental health, college students, felt need, mental health |
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2022;1:5
Original Article |
Dhanlakshmi B, Amita K, Prashantha K.
Prognostic Significance of Lymphatic Vessel Density by D2-40 Immune Marker and Mast Cell Density in Invasive Breast Cancer: A Cross Sectional Study at Tertiary Care Hospital in South India. |
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Abstract: Background: Tumour induced lymphangiogenesis plays a crucial role in metastasis and tumour progression. The intratumoural and peritumoral lymphatics are supposed to have different biological effects. The aim of present study was to investigate the correlation of intratumoral lymphatic vessel density (I LVD), peritumoral lymphatic vessel density (P LVD), intratumoral mast cell density (I MCD) and peritumoral mast cell density (P MCD) with prognostic parameters in primary breast carcinoma.
Methods: Lymphangiogenesis was detected using D2-40 monoclonal antibody and mast cell by using toludine blue stain in 50 cases of primary breast carcinoma. Positively stained lymphatic vessels were counted at 40 x in dense lymphatic vascular foci (hot-spot) within the tumour. Chi square, ANOVA test and Pearsons correlation was applied to determine the relationship amongst various variables, with statistical significance set at p <0.05.
Results: Mean P LVD was significantly higher than I LVD (6.25±21 vs 2.75±2.27,p <0.005). Significant correlation was noted between I LVD and P LVD and age, tumour laterality, tumour size and overall staging. However, there was no correlation between I LVD and P LVD with other important clinicopathologic prognostic markers like grade, lymphnode status and lymphovascular invasion. MCD was higher in both intratumoral and peritumoral location as compared to normal tissue. There was an association noted between P MCD with pathological staging and perineural invasion. However, there was no significant association of I MCD and P MCD with other prognostic markers like grade and lymphnode status. No significant correlation was noted between I LVD, P LVD, I MCD and P MCD.
Conclusion: The evidences from our study support the utility of D2-40 stain in determining the lymphatic density in IBC. The study findings also establish the existence of lymphangiogenesis in both intratumoral and peritumoral location. For now, the data presented herein do not permit us to promote the utility of LVD and MCD as predictors of prognosis in invasive breast carcinoma.
Key words: Mast cell, Lymphangiogenesis, Breast cancer, Prognostic factors |
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2022;1:6
Original Article |
Choudhary A, Avasarala S, Agrawal R, Tanwar GS, Poonia R.
Clinical and Etiopathological Correlation of Acute Infective Hepatitis and Fulminant Hepatic Failure in Pediatric Patients. |
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Abstract: Introduction: In India, infectious Hepatitis is one of the major health care burdens, with viral hepatitis being the most common culprit, followed by dengue, typhoid, and malarial hepatitis. Fulminant hepatitis manifests as a sudden abnormality in liver function enzymes in a child with no prior hepatic pathology.
Aims and Objects: This study was aimed at identifying the various etiological factors and correlating clinical features of viral hepatitis, and fulminant liver failure. Materials and Methods: This observational study was conducted in the paediatrics in-patient department of S.P. Medical College & P.B.M. Associated Group of Hospitals, Bikaner (Rajasthan) over a period of one year. A total of 125 children with a clinical and lab-confirmed diagnosis of acute infective hepatitis were included. Data including clinical signs, symptoms, and laboratory parameters were obtained and analyzed.
Results: Most commonly affected age group was between 5-10 years with the mean age being 7.1±4.6 years. The most common etiology was hepatitis A (n=39), followed by hepatitis E (n=24) and mixed hepatitis A virus (HAV)/hepatitis E virus (HAE) infection (n=20). Other causative organisms were dengue virus (n=16), typhoid (n=13), malaria (n=9), and hepatitis B. The most common clinical symptoms were fever, jaundice, loss of appetite, and vomiting/nausea. There were some clinical features seen more commonly in case of infection with certain organisms. High frequency of diarrhoea, arthralgia, and thrombocytopenia was seen with HAV. Neurological, renal complications and high mortality were associated with HEV or HAV/HEV co-infection. While retroorbital pain and purpuric rash were exclusive with dengue, malarial hepatitis was strongly associated with pallor and altered sensorium. Conclusion: Acute infective hepatitis is most commonly caused by HAV and HEV in Western Rajasthan. It is imperative to educate the masses regarding the prevention of common infections transmissible by infected drinking water, poor hand hygiene, improper waste disposal, and open defecation.
Key words: Viral hepatitis, fulminant liver failure, Children |
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2022;1:7
Original Article |
Srivastav S, Mardi K, Prasad V.
Spectrum of Reactive Morphological Alterations in Leucocytes in HIV Patients. |
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Abstract: Background: The earliest hematological manifestation of HIV infection can occur at the time of primary infection. Several peripheral blood abnormalities are known in HIV. However, not many studies have reported morphological changes in white blood cells in antiviral naïve patients and even fewer have compared them with HIV seropositive patients.
Material and methods: Peripheral blood smears from 100 patients were studied. 50 of them were newly diagnosed HIV seropositive cases and 50 were HIV seronegative. A peripheral blood smear was made to study morphology of various white blood cells A written informed consent was taken. Statistical analysis of the data obtained was done.
Results: Morphological abnormalities in the lymphocytes had been the most significant finding, which included nuclear lobulation, nuclear convolution and plasmacytoid and monocytoid features. Neutrophils also showed various morphological abnormalities. Most common were hypogranulation, hypersegmented nuclei and cytoplasmic vacuolations in descending order of frequency. Monocytes also revealed few morphological abnormalities including nuclear irregularities and cytoplasmic vacuolations.
Conclusion: The observations from this study will serve as a guide to clinicians as treatment of these patients should include supplements to monitor and improve these changes.
Key words: HIV, hematological, morphological, white blood cells |
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2022;1:8
Original Article |
Gupta S, Patheja S, Bansal RN.
Quantifying Maxillofacial Traumatic Injury for Holistic Management. |
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Abstract: Introduction: The maxillofacial region serves many essential functions of human body. Maxillofacial traumatic injury (MFTI) or sometimes called as facial trauma is the injury to the face, jaws and related structures such as head. Hard tissue / soft tissue injury may range from simple nasal bone fracture to gross facial comminution. The complex maxillofacial trauma has the potential to cause facial disfigurement and difficulty in jaw movement. This study focused on relationship between existing scoring systems as the clinical assessment for MFTI, as a tool for predicting prognosis, morbidity, social and psychological impact. Materials and Method: Data collection included demographics, etiology, MFTI clinical parameters, treatment and psychosocial loss. Data was obtained from the medical records, patient interview at each hospital visit and telephonic interviews as required. A predefined question was prepared containing closed and open ended questions and published scales. Results and conclusion: Mandibular fractures were observed in 69% MFTI cases of which 50% were mandibular only fractures. Need for holistic treatment and management approach was observed. Existing widely used FISS score was found to be predictor for few of the parameters only. Other factors required for holistic treatment approach and planning not predictable by FISS score have also been identified.
Key words: Maxillofacial traumatic injury (MFTI), withdrawal from social interaction, Health-Related Quality Of Life, Daily Living Activities, FISS score, Medicare |
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2022;1:9
Original Article |
Premakumar P, Azeez M, Sivakumar R, Deepa MS, Siraj SE.
Gender Determination Using Morphological Analysis of Palatal Rugae Patterns – A Retrospective Study. |
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Abstract: Background: Palatal rugae are unique for an individual and remain unchanged during individual's lifetime. Application of palatal rugae analysis as a method in gender identification needs to be confirmed with more scientific studies. The objectives of the present study were to assess the distribution of the palatal rugae patterns in Kerala population and compare the distribution of these parameters between males and females. Materials & Methods: A retrospective cross-sectional study was conducted by evaluating the casts of 100 dentate individuals, between the age of 18 and 30 years. The rugae were divided into two halves and patterns were then assessed as per Thomas and Kotze classification. Independent sample t-test was used to assess the significant difference of each type of palatal rugae between males and females. Results: Wavy rugae (mean – 5.6 ± 0.7) was predominant among males whereas curved (mean – 4.6 ± 0.6) and circular rugae (mean – 0.9 ± 0.3) were more in females, and were found to be statistically significant (p<0.05). The mean number of secondary rugae in females (1.5 ± 0.5) was greater than that of males (1.3 ± 0.4), and was found to be statistically significant (p<0.05). The diverging type was commonly found in females compared to males. Conclusion: Our findings showed statistically significant differences in the shapes and patterns of rugae between males and females among Kerala population. Thus, morphological analysis of palatal rugae can be considered as an additional aid in forensic odontology for gender differentiation.
Key words: Palatal rugae, Gender, Forensic dentistry, Palatoscopy |
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2022;1:10
Case Report |
Khanna R, Nayak D, Vasudevan G, Singh VK.
Malignant Melanoma Infiltrating the Bone Marrow. |
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Abstract: Malignant melanoma with infiltration into the bone marrow is seldom reported in the literature, for they are exceedingly rare. The primary site is not always apparent and a sizeable number of cases have been attributed to an occult primary. Metastasis to bone marrow is a terminal event usually occurring in stage IV of the disease and can be a focus of residual tumor cells which can cause a relapse.The current documentation is of a case of melanoma occurring as a rectal primary with anemia, thrombocytopenia, and leukoerythroblastic reaction. The marrow aspirates and trephine biopsy showed round to spindle-shaped malignant cells with intracytoplasmic brown-black coarse pigment, suggestive of melanin. The patient was diagnosed with stage IV melanoma but was lost for follow-up. The recognition of such an entity is important for both pathologists and clinicians alike. This case is being reported for the novelty of such an occurrence.
Key words: Malignant melanoma, bone marrow, leukoerythroblastic reaction, melanin |
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