Introduction
Modernization
and change in human lifestyle have proliferated
the prevalence of obesity and related
co-morbidities worldwide. Overweight or obesity is
a complex multifactorial disease defined by
excessive adiposity causing several
non-communicable diseases (NCDs) including
hypertension (1). Earlier, high adiposity was
considered a major health problem among the
developed countries and affluent societies.
However, it has now reached the stage of global
epidemic affecting even the middle-income and
low-income countries. In the WHO European region,
it has reached epidemic proportions affecting
almost 60% of adults causing a world-wide state of
alarm (1). Increased consumption of calorie-dense,
less nutritive foods combined with reduced
physical activity led to a rise in the incidence
of obesity since the 1980s, both in developed and
developing countries (2). According to World
Health Organization, high body mass index (BMI)
claims approximately 2.8 million lives each year
(3), while elevated blood pressure (BP) accounts
for about 7.1 million deaths worldwide, especially
among middle-aged and elderly adults (4).
Developing countries
like India, though known for the high prevalence
of under nutrition, now see a considerable
prevalence of overweight and obesity co-existing
among the population (5,6). It is alarming to note
that non-communicable diseases (NCDs), including
obesity and hypertension, are the leading causes
of death and are responsible for 74% of deaths
worldwide, and 66% of deaths in India and the
probability of premature mortality from NCDs was
22% (7). Further, based on the Global Burden of
Disease Study (GBD), Gupta and Xavier (8)
estimated that hypertension led to 1.6 million
deaths and 33.9 million disability-adjusted life
in 2015 and is the most important cause of
mortality and disease burden in India.
Excess fat
deposition and pulmonary hypertension (PH) are two
conditions that frequently co-exist in clinical
practice. A major upshot of being overweight
includes a higher prevalence of hypertension and a
cascade of cardiovascular diseases (CVDs). Several
studies (9–12) have shown sex differences in BMI
and BP, and the association between the two health
indicators in various populations worldwide. While
some studies (13,14) showed a higher prevalence of
obesity among men than their women counterparts,
other studies (15,16) have reported a higher
prevalence among women. On the other hand, males
were generally found to be more hypertensive than
females (12,17).
Bakir et al. (18)
reported that the published studies on obesity
have shown that the prevalence of obesity varies
significantly across the world, ranging between 15
percent to 60 percent among adults. Rural Indians
are no exception in this secular trend due to
nutritional transition and changes in lifestyle as
a consequence of urbanization. Tribal areas in
India are also seeing an increase in the
prevalence of non-communicable diseases due to
socio-economic changes and the adoption of modern
lifestyles (19). A systematic review on
hypertension in India by Anchala et al. (20)
reported that the pooled prevalence of
hypertension for rural North India, East India,
West India, and South India was 14.5%, 31.7%,
18.1%, and 21.1%, respectively, while eastern
India reported the highest prevalence equaling
that of numbers seen in urban parts of India.
Besides, there is a gap in the prevalence of
undiagnosed and untreated hypertension in rural
and urban areas, with education, co-morbidities,
tobacco usage, social group, work status, BMI,
religion, and physical activity being the
significant contributors in expanding the
rural-urban gap (21).
Northeast India,
being a tribal-dominated area, is the least
developed compared to other parts of India in
terms of infrastructure, connectivity, and
technology. The majority of this region's
indigenous population still relies on the
traditional agriculture-based economy. As such, a
lower prevalence of lifestyle-related diseases may
be expected. Yet, the National Family Health
Survey (NFHS-4) 2015-2016 (22) reported the
prevalence of hypertension in men to be 23.6% and
16.8% in females in Nagaland. The prevalence
increased in the following report (23), becoming
28.7% in males and 22.3% in females. It may also
be noted that, according to the Ministry of Health
and Family Welfare (24), in northeast India,
Nagaland has the third highest prevalence of
hypertension among men (23.6%) and women (16.8%)
aged between 15-49 years, with Sikkim having the
highest prevalence in both male (30.9%) and female
(18.4%). Previous studies (25,26) in this region
have reported a high prevalence of undernutrition
in different ethnic groups. Nevertheless, numerous
recent findings in similar fields by other
researchers have reported the prevalence of
obesity and hypertension in both adults and
adolescents among different tribal groups of the
region (27–31). Hence, like other regions of the
country, Northeast India also faces the double
burden of undernutrition and overnutrition.
The health of an
individual is significantly influenced by the
environment they live in. Therefore, hypertension
and obesity correlate to several modifiable
socio-economic determinants, such as occupation,
income, education, lifestyle, living standard,
etc. According to Shahraki et al. (32), the
possible explanations for obesity are educational
level, multiple pregnancies, marital status, and
lack of exercise. Similar observations of
socio-economic and behavioral factors impacting
obesity and hypertension are reported in various
studies (33–35).
With these views and
facts in mind, the current study was conducted
with the following three-fold aims: (a) to report
the prevalence of obesity and hypertension, (b) to
assess the relationship between BMI and BP, and
(c) to examine the effect of socio-economic and
demographic factors on obesity and hypertension.
Samples and Methods
The
Chakhesang Nagas
The Northeastern
region in India is one of the most culturally
diverse regions in the country, comprising of
eight states viz., Arunachal Pradesh,
Assam, Manipur Meghalaya, Mizoram, Nagaland,
Sikkim, and Tripura. There are over 145 tribal
communities in this region alone (36). The
Chakhesang Naga tribe is one of the major tribal
communities in Nagaland state. They are
geographically concentrated in the hills of the
Phek district. They belong to the Mongoloid
ancestry and the language spoken by them belongs
to the Sino-Tibetan family (37).
According to the
Census of India (38), the total population of the
Chakhesang Nagas is 1,54.874, of which, 1,22,767
individuals reside in rural areas, while 32,107
people are located in urban areas. The Chakhesang
families are nuclear to a large extent (97.5%),
having an average family size of 5.2 individuals
per family (39). The main occupation of the
Chakhesang Nagas is agriculture. Sükrünye
is the most important festival of the Chakhesang
tribe, which is celebrated by performing various
rituals for the purification and sanctification of
the body and soul. Like other Naga tribes, the
lineage system of the Chakhesang Nagas is
patrilineal. Traditionally, the division of labor
was based on sex and age. Men in this community
were warriors, and their role was to protect the
women, children and their village from potential
neighboring enemies. Men were primarily involved
in hunting, village administration, trade and
business, while the role of women were household
work, agriculture-related work, child rearing and
food gathering practices (39). However, in the
present age, although men may have a higher social
status in society, women, too, have significant
power in decision-making and managing finances in
the family.
Study design
and data collection
The present study is
a cross-sectional study conducted among the
Chakhesang adults from five villages of Phek
district in Nagaland, Northeast India. Data were
collected from a sample of 209 adults (102 females
and 107 males) aged between 18 and 50. Care was
taken to include only healthy participants in the
study. Before data collection, verbal consent was
obtained from the respective village Headmen.
Written informed consent in both English and local
dialect was obtained from each participant. Also,
the purpose of the study and the principles of
ethical standards according to Helsinki
Declaration were carefully elaborated to the
participants.
Anthropometric
and physiological measurements
Data on height and
weight was collected following appropriate
techniques given by the International Society for
the Advancement of Kinanthropometry (40). Data on
systolic BP (SBP) and diastolic BP (DBP) were
collected using a mercury sphygmomanometer. BP was
measured with the participant in a sitting
position. The participants were allowed to rest
for about five minutes to recover from recent
activities and apprehension. BP was then measured
twice with a minimum gap of two minutes between
the measurements, and the average was taken.
Utmost care was taken to ensure that all the
anthropometric and BP measurements were taken
before a heavy meal.
Definitions
The nutritional
status of the present population was classified
using the criteria given by WHO (41) for Asian
adults. Accordingly, the body mass index (BMI) was
classified as follows- Underweight = ≤18.5 kg/m2,
Normal weight = 18.5-22.9 kg/m2,
Overweight = 23-27.4kg/m2 and Obese =
≥27.5kg/m2. BP was classified based on
the classification of the Joint National Committee
VII Report (42). Accordingly, BP categories were
grouped as follows- Normal = <120/80 mmHg,
Pre-hypertension = 120-139/80-89 mmHg, and
Hypertension = ≥140/90 mmHg. In the present
investigation, Hypertension I (140-159/90-99 mmHg)
and Hypertension II (≥160/100 mmHg) were pooled
together as Hypertension. Mean arterial pressure
(MAP) was calculated using the formula- MAP = DBP
+ (SBP – DBP)/3. This formula, given by Haque and
Zaritsky (43), assumes that one-third of the
cardiac cycle is spent in the systole.
Demographic
and socio-economic information
Socio-economic and
demographic parameters included in the present
study are, age, sex, marital status, family size,
occupation, education, and income. Data on these
parameters were collected by interviewing the
participants using an interview schedule. Marital
status was grouped into three categories: Married,
Unmarried, and DSW (Divorced/Separated/Widowed).
Family size was pooled into three categories viz.,
Small (1-3 members), Medium (4-6 members), and
Large (>6 members). Occupation was categorized
into three groups viz., Group I (Farmers
and daily wagers), Group II (Government/private
sector employees and entrepreneurs), and Group III
(Homemakers, students and currently not working).
Education levels were grouped into three levels viz.,
Level I (Matriculation and below), Level II
(Post-matriculation to undergraduate), and Level
III (Graduate and above). Lastly, income groups
were classified based on per capita income
following the percentile method given by United
Nations (44). Suitably, the income groups for this
population were classified as follows- Low-income
group/LIG (<50th percentile = ≤2500
INR), Middle-income group/MIG (50th to
75th percentile = 2501-5000 INR), and
High-income group/HIG (>75th
percentile = >5000 INR).
Statistical
analysis
This paper's
statistical analyses were computed using the
Statistical Package for Social Sciences (SPSS)
software (version 26.0) for Windows. Descriptive
statistics in the form of mean, standard
deviation, and percentage were computed. The
difference between two proportions was calculated
using t-test and chi-square test. The difference
between more than two proportions was calculated
using the analysis of variance (ANOVA) test.
We utilized linear
regression and logistic regression models to
assess the relationship between nutritional status
and BP. In the linear regression model, SBP, DBP,
and MAP were dependent variables, while BMI was
independent. For the binary logistic regression
(BLR) model, the dummy variable was 1 for those
who are hypertensive and 0 for those who are not.
Finally, multivariate multiple regression (MMR)
analysis was done to assess the effects of
socio-economic and demographic factors on BMI and
BP. In this model, all the dependent variables viz.,
BMI, SBP and DBP were considered simultaneously.
All the covariates viz., age, sex,
marital status, family size, occupation, education
level, and income group were recorded as dummy
variables. The dummy variables for these
covariates are as follows-
- Age: 1 = Younger adults, 2 = Older adults
- Sex: 1 = Female, 2 = Male
- Marital status: 1 = Married (DSW included), 2
= Unmarried
- Family size: 1 = Small (1-5 members), 2 =
Large (>5 members)
- Occupation: 1 = Labour based 2 = Non-labour
based
- Education level: 1 = Lower (till
matriculation), 2 = Higher (above matriculation)
- Income group: 1= LIG (≤5000 INR per capita), 2
= HIG (>5000 INR per capita)
In the MMR analysis, we used the general model
(GM), including all tested independent variables,
and the most parsimonious model (MPM), including
only statistically significant independent
variables from the GM.
Results
Socio-economic
and demographic background
Background
information on the socio-economic and demographic
characteristics of the presently studied
population is presented in Table 1. Concerning
age, younger adults comprise 55.0% of the total
sample, while older adults comprise 45.0%. The
percentage frequencies of married, unmarried, and
DSW individuals are 46.9%, 45.5%, and 7.7%,
respectively. On the accounts of family size,
medium family size (44.5%) was highest, followed
by large family size (34.4%) and least by small
family size (21.1%). Most of the people in this
population are working as farmers and daily wagers
(46.9%), which requires a lot of physical
activity. Entrepreneurs, government, and private
sector employees account for 32.5% of the total
sample. In terms of education level, below
matriculation (46.9%) was found to be the highest,
followed by post-matriculation (32.5%), while
about 20.6% were found to have graduated college.
Furthermore, the percentage frequencies of LIG,
MIG, and HIG, were 41.6%, 34.9%, and 23.4%,
respectively.
Table 1: Demographic and
socio-economic profile of the study
population
|
Socio-demographic variables
|
Categories
|
N
|
%
|
Age
|
Younger adults (18-34 years)
|
115
|
55.0
|
Older adults (35-50 years)
|
94
|
45.0
|
Sex
|
Female
|
102
|
48.8
|
Male
|
107
|
51.2
|
Marital status
|
Married
|
98
|
46.9
|
Unmarried
|
95
|
45.5
|
Divorced, Separated, Widow (DSW)
|
16
|
7.7
|
Family size
|
Small (1-3 members)
|
44
|
21.1
|
Medium (4-6 members)
|
93
|
44.5
|
Large (>6 members)
|
72
|
34.4
|
Occupation group
|
Group 1 (Farmers and daily wagers)
|
98
|
46.9
|
Group 2 (Entrepreneurs, Govt. and Pvt.
sectors)
|
68
|
32.5
|
Group 3 (Homemakers, students, and not
working)
|
43
|
20.6
|
Education levels
|
Level 1 (Matriculation and below)
|
98
|
46.9
|
Level 2 (Post-matriculation to
undergraduate)
|
68
|
32.5
|
Level 3 (Graduation and above)
|
43
|
20.6
|
Income groups
|
LIG (≤2500 INR)
|
87
|
41.6
|
MIG (2501 – 5000 INR)
|
73
|
34.9
|
HIG (>5000 INR)
|
49
|
23.4
|
Figure legends: LIG = Low-income group,
MIG = Middle-income group, HIG =
High-income group, INR = Indian rupees
|
Anthropometric and physiological
characteristics
Descriptive
statistics of anthropometric and BP measurements
of the Chakhesang adults are illustrated in Table
2. Chakhesang males are significantly taller
(164.71 cm Males vs. 154.63 cm Females) and
heavier (65.03 kg Males vs. 55.98 kg
Females) than their female counterparts
(p<0.001). BMI was also higher among males
(23.91 kg/m2) than females (23.41 kg/m2),
albeit with an insignificant variation. Both SBP
and DBP were found to be significantly (p<0.05)
higher among Chakhesang males (131.43 mmHg SBP and
83.63 mmHg DBP) than their female counterparts
(125.80 mmHg SBP and 79.70 mmHg DBP). Similarly,
the mean MAP was higher in males (99.57 mmHg) than
the females (95.07 mmHg) at p<0.05.
Table 2: Descriptive statistics
of anthropo-physiologic measurements
among the Chakhesang adults, by sex
|
Measurements
|
Females (N=102)
|
Males (N=107)
|
Total (N=209)
|
t-values
|
Mean
|
SE
|
Mean
|
SE
|
Mean
|
SE
|
Stature (cm)
|
154.63
|
0.57
|
164.71
|
0.51
|
159.80
|
0.51
|
-13.683**
|
Weight (kg)
|
55.98
|
0.79
|
65.03
|
0.98
|
60.61
|
0.70
|
-7.102**
|
BMI (kg/m2)
|
23.41
|
0.33
|
23.91
|
0.33
|
23.67
|
0.23
|
-1.062NS
|
SBP (mmHg)
|
125.80
|
2.05
|
131.43
|
1.94
|
128.68
|
1.42
|
-1.989*
|
DBP (mmHg)
|
79.70
|
1.20
|
83.63
|
1.25
|
81.71
|
0.88
|
-2.252*
|
MAP (mmHg)
|
95.07
|
1.42
|
99.57
|
1.38
|
97.37
|
1.00
|
-2.265*
|
Figure legends: NS = Not
significant, * p<0.05 **
p<0.001
|
Prevalence of obesity and hypertension
Sex-wise
distribution of the prevalence of
overweight/obesity and hypertension among the
Chakhesang adults is shown in Table 3. The overall
prevalence of overweight and obesity are 42.6% and
13.4%, respectively. Males exhibited a higher
prevalence of overweight (43.0% Males and 42.2%
Females) and obesity (15.0% Males and
11.8% Females) as compared to the females, albeit
insignificant variation. It is also interesting to
see that the percentage frequency of underweight
(3.8%) individuals in this population is minimal.
Regarding BP, the overall prevalence of SBP
hypertension was 22.5%, and that of DBP
hypertension was 28.2%. Chakhesang males showed a
significantly higher prevalence of SBP
hypertension (27.1% Males vs. 17.6% Females) than
their female counterparts (p<0.05). DBP
hypertension also showed similar gender
differences (31.8% Males and 24.5% Females), yet,
this variation was statistically insignificant.
Table 3: Nutritional status and
blood pressure categories of Chakhesang
adults, by sex
|
Parameters
|
Categories
|
Females
|
Males
|
Total
|
χ2-values
|
n
|
%
|
N
|
%
|
n
|
%
|
BMI
|
Underweight
|
5
|
4.9
|
3
|
2.8
|
8
|
3.8
|
1.343NS
|
Normal weight
|
42
|
41.2
|
42
|
39.3
|
84
|
40.2
|
Overweight
|
43
|
42.2
|
46
|
43.0
|
89
|
42.6
|
Obese
|
12
|
11.8
|
16
|
15.0
|
28
|
13.4
|
SBP
|
Normal
|
49
|
48.0
|
31
|
29.0
|
80
|
38.3
|
8.266*
|
Pre-hypertension
|
35
|
34.3
|
47
|
43.9
|
82
|
39.2
|
Hypertension †
|
18
|
17.6
|
29
|
27.1
|
47
|
22.5
|
DBP
|
Normal
|
56
|
54.9
|
55
|
51.4
|
111
|
53.1
|
1.494NS
|
Pre-hypertension
|
21
|
20.6
|
18
|
16.8
|
39
|
18.7
|
Hypertension †
|
25
|
24.5
|
34
|
31.8
|
59
|
28.2
|
Figure legends: † = Hypertension I and
II; NS = Not significant; *
= p<0.05
|
Association of nutritional status with
blood pressure
Sex-wise
distribution of BP in different categories of
nutritional status among the Chakhesang adults is
given in Table 4. In all the BP traits, the mean
values in both sexes show an increasing trend as
BMI rise. The ANOVA test used for assessing the
association between BP values and nutritional
status presented significant figures in all the
traits considered. Further, the linear regression
analysis (Table 5) revealed that a unit rise in
BMI significantly increases SBP, DBP, and MAP by
2.32 mmHg, 1.82 mmHg, and 1.99 mmHg, respectively.
The R2 values explain about 14.6%,
23.7%, and 21.7% of high SBP, high DBP, and high
MAP, respectively, as a consequence of an increase
in BMI.
Table 4: Distribution of blood
pressure in different categories of
nutritional status among the Chakhesang
adults, by sex
|
Nutritional status
|
Statistics
|
Females
|
Males
|
SBP (mm/Hg)
|
DBP (mm/Hg)
|
MAP (mm/Hg)
|
SBP (mm/Hg)
|
DBP (mm/Hg)
|
MAP (mm/Hg)
|
Underweight
|
Mean
|
108.80
|
66.40
|
80.53
|
117.33
|
67.33
|
84.00
|
SE
|
3.72
|
5.52
|
4.08
|
3.52
|
1.76
|
2.03
|
Normal weight
|
Mean
|
118.11
|
73.64
|
88.46
|
126.47
|
80.23
|
95.65
|
SE
|
2.91
|
1.46
|
1.87
|
3.02
|
1.89
|
2.17
|
Overweight
|
Mean
|
130.76
|
84.18
|
99.71
|
133.13
|
84.71
|
100.85
|
SE
|
2.95
|
1.73
|
2.05
|
3.12
|
1.88
|
2.02
|
Obese
|
Mean
|
142.00
|
90.41
|
107.61
|
142.25
|
92.50
|
109.08
|
SE
|
6.03
|
2.00
|
3.05
|
3.80
|
2.78
|
3.02
|
ANOVA
|
7.427
|
14.836
|
12.260
|
3.163
|
5.792
|
5.282
|
p-values
|
<0.001**
|
<0.001**
|
<0.001**
|
0.028*
|
0.001*
|
0.002*
|
Figure legends: * = p<0.05
** = p<0.001
|
Table 5: Linear regression
analysis showing the relationship
between BMI and blood pressure among the
Chakhesang adults
|
Variables
|
BMI Predictor
|
β-coefficient
|
Standard error
|
R2
|
p-values
|
SBP
|
2.32
|
0.39
|
0.146
|
<0.001
|
DBP
|
1.82
|
0.22
|
0.237
|
<0.001
|
MAP
|
1.99
|
0.26
|
0.217
|
<0.001
|
Furthermore, after
adjusting for age and sex, results of the BLR
analysis showing the relationship between
hypertension and nutritional status is shown in
Table 6. It is seen that, overweight individuals
are at 2.52 times (systolic) and 2.24 times
(diastolic) higher risk to develop hypertension
than their normal weight counterparts (p<0.05).
On the other hand, the odds of developing systolic
hypertension by obese adults in this community is
7.34 as compared to the reference group
(p<0.001). Likewise, obese BMI was found to
pose 7.70 times increased risk for developing
diastolic hypertension than normal BMI
(p<0.001).
Table 6: Binary Logistic
regression (BLR) showing the association
of nutritional status with hypertension
among the Chakhesang adults†
|
Nutritional status
|
Systolic hypertension
|
Diastolic hypertension
|
OR
|
95% CI
|
p-values
|
OR
|
95% CI
|
p-values
|
Normal ®
|
1.00
|
-
|
-
|
1.00
|
-
|
-
|
Overweight
|
2.52
|
1.02-6.24
|
0.045*
|
2.24
|
1.03-4.87
|
0.043*
|
Obese
|
7.34
|
2.45-21.97
|
<0.001
|
7.70
|
2.78-21.33
|
<0.001
|
Figure legends: † Adjusted for age and
sex, * = p<0.05, OR = Odds ratio, CI =
Confidence Interval, ® = Reference
Category
|
Impact of socio-demographic and economic
factors on obesity and hypertension
Table 7 presents the
results of the MMR analysis depicting the impact
of socio-economic and demographic factors on
nutritional status and BP through the GM, which
includes all the tested variables, and the MPM,
which includes only statistically significant
variables. The GM shows that the variation that
can be explained through the selected confounding
variables was ~20.0% for BMI, ~18.7% for SBP, and
~20.2% for DBP. Age was found to be the most
crucial confounder of BMI, SBP, and DBP (Table 7).
More specifically, Chakhesang adults in the higher
age group showed a higher prevalence of
overweight/obesity and hypertension. Additionally,
gender differences in BP were also observed, with
the males showing a higher tendency to become
hypertensive than the females in both SBP and DBP
(p<0.05).
Further, nutritional
status was significantly associated with income
(p<0.05), occupation (p<0.001), and
education (p<0.05) (Table 7). As evident from
the positive β-coefficient values, higher BMI was
associated with higher income and occupation not
involving physical labour. In contrast, higher
education was found to be a significant
(p<0.05) protective factor for increased BMI,
as seen from the negative β-coefficient value.
From the MPM, it is seen that age (p<0.05),
income level (p<0.05), occupation (p<0.001),
and education level (p<0.05) can explain ~19.1%
of the total variation in BMI. Concerning BP,
education was found to have a significant negative
impact on SBP (p<0.05) (Table 7). In other
words, people of this community with higher
education show lesser vulnerability to becoming
hypertensive in SBP. At the same time, higher
income was found to be significantly associated
with higher DBP (p<0.05), as apparent from the
positive β-coefficient value. Additionally, from
the MPM, we see that age (p<0.001) and sex
(p<0.05) alone can explain ~ 15.3% of the total
variance in systolic hypertension. While the three
confounding variables, viz., age
(p<0.001), gender (p<0.05), and income level
(p<0.05), can explain ~18.9% of the variation
in DBP.
Table 7: Multivariate multiple
regression (MMR) analysis showing the
impact of selected socio-demographic
parameters on BMI and BP among the
Chakhesang adults.
|
Variables
|
Confounding variables
|
General Model (GM)*
|
Most Parsimonious Model (MPM)*
|
β
|
SE
|
Sig
|
β
|
SE
|
Sig
|
BMI
|
Age group (YA vs. OA)
|
1.076
|
0.509
|
0.036
|
1.150
|
0.476
|
0.017
|
Sex (Female vs. Male)
|
0.642
|
0.438
|
0.144
|
|
|
|
Marital status (M vs. UM)
|
-0.136
|
0.377
|
0.719
|
|
|
|
Family size (Small vs. Large)
|
0.019
|
0.331
|
0.955
|
|
|
|
Income levels (LIG vs. HIG)
|
0.793
|
0.349
|
0.024
|
0.781
|
0.313
|
0.013
|
Occupation (LB vs. NLB)
|
2.297
|
0.578
|
<0.001
|
2.293
|
0.565
|
<0.001
|
Education levels (Low vs. High)
|
-1.133
|
0.360
|
0.002
|
-1.062
|
0.349
|
0.003
|
Multiple R2
|
0.200
|
0.191
|
SBP
|
Age group (YA vs. OA)
|
13.496
|
3.115
|
<0.001
|
13.443
|
2.840
|
<0.001
|
Sex (Female vs. Male)
|
6.673
|
2.680
|
0.014
|
6.860
|
2.688
|
0.011
|
Marital status (M vs. UM)
|
3.987
|
2.306
|
0.085
|
|
|
|
Family size (Small vs. Large)
|
-0.576
|
2.025
|
0.776
|
|
|
|
Income levels (LIG vs. HIG)
|
2.752
|
2.138
|
0.200
|
|
|
|
Occupation (LB vs. NLB)
|
3.775
|
3.540
|
0.288
|
|
|
|
Education levels (Low vs. High)
|
-5.049
|
2.206
|
0.023
|
|
|
|
Multiple R2
|
0.187
|
0.153
|
DBP
|
Age group (YA vs. OA)
|
7.963
|
1.905
|
<0.001
|
9.158
|
1.625
|
<0.001
|
Sex (Female vs. Male)
|
4.618
|
1.639
|
0.005
|
4.100
|
1.602
|
0.011
|
Marital status (M vs. UM)
|
0.016
|
1.410
|
0.991
|
|
|
|
Family size (Small vs. Large)
|
0.334
|
1.238
|
0.788
|
|
|
|
Income levels (LIG vs. HIG)
|
2.773
|
1.308
|
0.035
|
2.365
|
1.030
|
0.023
|
Occupation (LB vs. NLB)
|
1.704
|
2.165
|
0.432
|
|
|
|
Education levels (Low vs. High)
|
-2.431
|
1.349
|
0.073
|
|
|
|
Multiple R2
|
0.202
|
0.189
|
Figure legends: * = Significant p-values
are highlighted in bold, YA = Younger
adults, OA = Older adults, M = Married, UM
= Unmarried, LIG = Low-income group, HIG =
High-income group, LB = Labor based, NLB =
Non-labor based
|
Discussion
Lifestyle-related
NCDs are a growing worldwide phenomenon;
therefore, it has become vital to understand their
social, economic, behavioral, and demographic
correlates at the community level. The present
study attempts to examine the prevalence of
obesity and hypertension in a tribal population in
India, emphasizing their association with selected
socio-economic and demographic parameters.
Our study depicts
that Chakhesang males were significantly taller,
heavier, and showed higher BP readings than their
female counterparts. As a result, over-nourished
nutritional status and high BP is more prevalent
among the males than the females in this tribe.
This finding on gender disparity among the
Chakhesang adults aligns with results on other
populations in India (14,45,46). On the other
side, our finding on sex difference contradicts
other literature that reported females to be more
vulnerable to obesity and hypertension (16,19,47).
Hence, gender variation in terms of obesity and
hypertension is inconsistent as it may have to do
with community-specific gender roles in different
societies.
The prevalence of
obesity (13.4%) and hypertension (25.4%, SBP and
DBP combined) in this tribal community is
relatively high. Recent studies in Northeast India
have also reported the prevalence of obesity and
hypertension in different tribal groups viz.,
Zou (28), Rengma (5), Mising (14), Khasis (30),
Tangkhul (48), Rongmei (29), Hmar (49), and Angami
(13). Thus, we see that the cases of obesity and
hypertension are on the rise even among the
neglected tribal populations in the region. This
is probably because of the shift from an agrarian
society to a more urban lifestyle.
Although the present
study fails to examine the rural-urban dichotomy
in the prevalence of obesity and hypertension, our
findings suggest an appallingly high prevalence of
these two NCDs among the Chakhesangs in a rural
setting. Majority of the people in this community
are overweight (56%) according to the Asian Indian
BMI cut-off values given by WHO (41). Such a
scenario is rare in the tribal population of
India, especially in rural areas. For instance,
the combined prevalence of overweight and obesity
among rural Hmars was 24.4% (50), among rural
Angamis was 25% (19), and rural Rongmei Nagas was
41% (29). Similarly, the prevalence of
hypertension (25.5%) in the current study was also
found to be very high compared to other rural
populations of India. For instance, the prevalence
of hypertension among rural Indian adults based on
NFHS-4 data was 15.5% (45), among rural Khasi
women was 8.65% (30), and among rural Hmars was
17.4% (50). Hence, the present study’s findings
show a ridiculously high prevalence of both
overweight and hypertension for a rural settlement
compared to other rural populations in the
country. A previous study by Longvah et al. (39)
conducted among the Chakhesang women reported 12%
of overweight and 18% of hypertension which is
much lower as compared to the women of the present
study (54% Overweight and 21.1% Hypertensive). In
this connection, it may be noted that hypertension
in low- and middle-income countries has increased
between 1990 and 2020 in both urban and rural
areas, but with a stronger trend in rural areas
(51). Thus, our findings on incidences of high BP
strongly supplements to such a secular trend.
The association of
obesity and hypertension has much caught the
attention of epidemiological researchers. Using
various statistical tools, our study revealed that
BP increased in both sexes with a rise in BMI.
Thus, overweight and obese people in this
community are more susceptible to becoming
hypertensive than their normal-weight
counterparts. This positive association of
nutritional status with BP largely commensurate
with the broader literature. Major researches
which showed BMI as a critical indicator of
hypertension risks were reported among American
Adults (52), Chinese adults (53), and African and
Asian adults (54). Contradicting these findings
reported worldwide and in the present study, no
significant association between BMI and BP was
found among the Cameroonians (9) and eight tribal
communities in India (55).
Our study reported
age as one of the most critical confounders of BMI
and BP. The MMR analysis shows older adults at
higher risk of developing obesity and high BP than
younger adults. More specifically, Chakhesang
Nagas tend to become hypertensive and accumulate
higher adiposity as age advances. This trend is
true to a large extend even in other studies
conducted by various researchers (13,48,56,57).
However, few studies in India have reported no
significant effect of age on BMI (28,58).
Conversely, BP seems to universally increase with
increment in age. This is because as one grows
older, there are structural changes in the
arteries, making them stiffer, thus causing BP to
rise (59).
The impact of
socioeconomic factors on adiposity and BP shows
variant results in different populations. In
developed countries, higher socioeconomic status
(SES) is greatly associated with lower incidences
of CVDs. For instance, cardiovascular health is
worst in lower SES groups among the American (60)
and Spanish (61) populations. However, in
developing countries like India, higher SES is
linked with higher CVDs, including obesity and
hypertension as seen in numerous studies
(33,47,62). Our findings depict that income,
occupation and education were the important
significant confounders of obesity and
hypertension among the Chakhesang adults.
Precisely, Chakhesang adults placed in the higher
income group are more vulnerable to developing
both obesity and high BP, while people involved in
non-labor based occupation are more susceptible to
becoming obese. People of this community involved
in non-labor based occupations are mostly
white-collar job holders and entrepreneurs having
higher incomes than the agriculturalists and daily
wagers. Perhaps, the people employed in government
and private sectors perform lesser physical
activity and can afford higher calorie food which
may have accelerated the BMI and BP readings in
this population. This suggests that, like majority
of the works reported in India, cardiovascular
health is worst in higher SES even among the
Chakhesang tribe. A similar effect of income was
reported in a multi-tribal population study in
India (33), while Rengma et al. (5) found the
association of both income and occupation on BMI
among the Rengma Nagas of Assam, alike to the
present findings. On the other hand, some recent
studies (13,46) in the country couldn’t detect the
impact of socio-economic factors on cardiovascular
risks.
Education is widely
considered to ameliorate the risk of CVDs in
high-income countries (62). Although incomparable,
the present population intriguingly shows a
similar trend of education effect on BMI and BP
with other higher-income countries like America
(52), Spain (61), and Denmark (63), where
hypertension risk is worst in people with low
education. More precisely, education had a
negative impact on nutritional status and BP,
indicating that Chakhesang adults placed in the
higher education level had lower BP than their
counterparts who are placed in the lower education
level. This is perhaps because Chakhesang adults
who have higher education are more sensitized
about the causes, risks, management, and treatment
of hypertension. This finding on education in the
present population contradicts the findings on
other neighboring populations of Northeast India viz.,
the Misings tribe (14) and the Rengma tribe (5),
and other communities from other parts of India
(33,62).
Chakhesang Nagas are
also well known for their high consumption of pork
meat, high salt intake, and high consumption of
locally brewed rice beer (hezo). Pork
meat has a high content of fats, while hezo
has a high content of carbohydrates and alcohol.
Regular consumption of these two components by the
people might have raised body fat levels leading
to higher cases of obesity which ultimately spiked
up the BP. A recent study by Tsukru and Ghosh (14)
in the neighboring population of Mising tribe have
reported a similar impact of pork fat consumption
and traditionally processed rice beer on BMI and
BP. Also, high sodium intake has been linked to
hypertension yet the frequency of high salt intake
has been on the rise in many populations worldwide
(64). In this view, it is interesting to note that
a previous study by Longvah et al. (39) on the
same population revealed that the salt intake in
this particular community was 8.3g/day which was
higher than the WHO (64) recommended level of
<5g/day. Such a high salt intake on a regular
basis could have spiked the BP in the current
study. However, the effects of extra salt intake
along with high pork meat intake and hezo
consumption on obesity and hypertension among the
Chakhesang Nagas needs to be further investigated
at the micro-nutrient level. Other indigenous
communities in Northeast India too have shown a
similar impact of extra salt intake on BP
(33,47,65). Furthermore, Dixit and Dhakad (66)
suggests that even a moderate reduction in its
consumption in the general population would bring
about a change in the health aspect reversing 8.5
million cardiovascular-related deaths within a
time interval of ten years.
In this field of
research, tribal populations in Northeast India
furnish a fascinating epidemiological window,
since previous studies (25,26) over the past have
shown higher prevalence of undernutrition.
Moreover, the prevalence of hypertension and
obesity among the tribals has particularly
intrigued the scientific community as it exhibits
a transition from rural to urban lifestyle. It may
also be noted that, Naga tribes are disadvantaged
communities listed in the Indian Constitution
under Article 342 by the Government of India (67).
In the past, the Chakhesang tribe was by and large
an agrarian society practicing primitive
technology-based agriculture which required a lot
of physical activities. But, with the uproar of
modernization and urbanization processes, a lot
have changed in this community. Many people are
now engaged in white-collar jobs in the government
and private sectors, entrepreneurship, and other
income-generating activities like floriculture,
farming, weaving, basketry, construction, daily
wage labor, etc. Hence, as also evident
from the impact of socio-economic factors in the
present study, the high prevalence of
overweight/obesity and hypertension among the
Chakhesang adults can be attributed to
urbanization, which led to a more sedentary
lifestyle and changes in dietary patterns upon
adoption of modern lifestyle.
Conclusion
The prevalence of
overweight/obesity and hypertension in this tribal
community is appallingly high for a rural setting.
Age, gender, income, occupation, and education
were found to be the most crucial
socio-demographic determiners of obesity and
hypertension among the Chakhesang adults.
Transition from the traditional agrarian economy
to non-agricultural economy, have improved the
socio-economic position and lifestyle of this
tribal community which has ultimately resulted in
worsening their cardiovascular health.
Additionally, improving the educational status and
reducing the daily salt intake in this community
might significantly reduce the risks of obesity
and hypertension in this population. Hence, our
findings call for robust screening, earliest
detection, and awareness starting from rural
household levels.
Limitations of the study
Our investigation
was unable to assess the impact of dietary intake
habits (specifically, high pork fat consumption
and high salt intake in this tribal community) and
behavioral factors (specifically, alcohol and
tobacco consumption) which are considered to be
the major contributors to cardiovascular risks.
Acknowledgements
The authors thank
all the Chakhesang participants for their
cooperation in the present study. NN and VT would
like to thank Mr. Venuvoto Theluo and his parents
for their unceasing hospitality, accommodation,
help, and care rendered during our fieldwork. The
authors are thankful to the Department of
Anthropology, North-Eastern Hill University, for
conducting the fieldwork.
Conflicts of interest
The authors declare that there are no conflicts
of interest.
Source of funding
The authors did not receive any funding for this
study.
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