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Volume-9 (2010);
Issue 3 (July-September)
Published on Oct 15, 2010
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2010;3-1
Editor's Note |
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Editor's Note |
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This Article |
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2010;3-2
Original Article |
Sankapithilu
GB, Nagaraja V, Khan MA.
A study of factors
delaying hospital arrival and predictors of mortality in patients presenting
to emergency department with Stroke: A developing state scenario. |
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Abstract: Background: Thrombolytic therapy
for acute ischemic stroke has recently become available in India but
its success depends on initiating the treatment in the narrow therapeutic
time window. There is commonly a delay of several hours before patients
with acute stroke seek medical attention. Materials and Methods:
A prospective study was conducted to assess the factors influencing
this delay in admission of acute stroke cases. 134cases (101 males,
33 females) of acute stroke that arrived within 72 hours at our hospital
casualty were recruited. A standardized structured questionnaire was
given to patients or their attendants. Results: The median
time to casualty arrival was 9 hours with 13.4% cases arriving within
3 hours and 36.5 % cases within 6 hours. Distances from hospital, referral,
belief in myths and alternate medicine and low threat perception of
symptoms of stroke were independent factors associated with delay in
arrival. Living in city, day time onset, urgency shown by attendant,
availability of transport and presence of family history were associated
with early arrival. There was no correlation with patients' or attendants'
sex, educational status, history of previous stroke or transient ischemic
attack, subtype or severity of stroke, time of stroke and availability
of transport. 134 patients (65.7% were from rural population, 55.22%-smokers,
46.76%-alcoholics) with mean (SD) age of 53.83+/-18.02years [significantly
lower in females (mean difference=9.73years p=0.002)], were admitted
and diagnosed to have stroke. 87.3% had first episode of stroke and
12.7 had more than one episode of stroke. ICF rate was 26.1%. ICF rate
has no relation with age (p=0.516), sex (p=0.460), number of episodes
(0.795), underlying hypertension (p=0.905). Odds of diabetics dying
were 12 times higher than non-diabetics. Inpatient mortality was also
significantly higher in smokers compared with non-smokers (p=0.004),
in patients with right-sided compared with left-sided hemiplegic (p=0.029)
and who couldn’t afford computed tomography (CT) scan (p=0.007). Kaplan
Meier curve in Image-1 shows the survival following admission to emergency
ward. Conclusion: Adequate
measures need to be taken to improve the public awareness of stroke
and the role of local doctors. Our study has shown that active smokers,
involvement of the right side and non performance of CT were independent
predictors of mortality which have not been shown earlier. Also, we
found that diabetes mellitus is independent predictor of mortality in
stroke, which has been seen in earlier studies too.
Key words: Epidemiology;
Stroke; Thrombolytic therapy |
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2010;3-3
Original Article |
Kumar A, Sivakanesan R.
Cardiovascular
Risk Factors in Normolipidemic Acute Myocardial
Infarct Patients on Admission – Do Dietary Fruits and Vegetables
Offer Any Benefits? |
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Abstract: Background:
Myocardial Infarction (MI) is a leading cause
of death in India. Whether dietary vitamins could reduce risk of cardiovascular
disease among Indians is still not clear and very few studies have addressed the association between dietary vitamin acting
as an antioxidant or pro-oxidant and its effect on risk reduction or
aggravation in normolipidemic AMI patients. Objective:
The goal of the current study was to address the association between
dietary vitamin and cardiovascular risk in normolipidemic acute myocardial
infarct patients compared with healthy controls. Design:
Dietary intake of vitamins was assessed by 131 food frequency questionnaire
items in both AMI patients and age/sex-matched controls. The associated
changes in risk factors due to antioxidant vitamins intake was also
assessed in normolipidemic acute myocardial patients and was compared
with controls. Results: Dietary intake
of vitamin A, B1, B2, B3 was significantly higher in AMI patients compared
to healthy controls but the intake of vitamin C was significantly higher
in controls compared to AMI patients. Even though the vitamins intake
was higher in patients, the associated cardiovascular risk factors were
not reduced compared to controls. The total cholesterol, LDL-c, TAG were
significantly higher (p<0.001) in AMI patients except HDL-c which
was significantly higher (p<0.001) in controls. The endogenous
antioxidants were found to be significantly lowered in patients compared
to controls in spite of higher vitamin intake. Similarly the enzymatic
antioxidants were also significantly lowered in patients. The mean serum
Lipoprotein (a) malondialdehyde (MDA) and conjugated diene (CD) levels
in patients were significantly elevated compared with controls. The
levels of caeruloplasmin, C-reactive protein, fibrinogen, ischemia-modified
albumin were significantly higher but arylesterase activities were lowered
in patients. Conclusion:
Diets rich in vegetables and fruits do not seem to reduce the cardiovascular
risk in normolipidemic AMI patients among Indians and Sri Lankans.
Key words: Dietary vitamins; Acute myocardial infarction; Cardiovascular risk factors;
Normolipidemia; India; Sri Lanka |
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This Article |
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2010;3-4
Original Article |
Balgir RS.
Intervention
and Prevention of Hereditary Hemolytic Disorders in Two Ethnic Communities
of Sundargarh District of Orissa, India: An Experience from KAP Studies. |
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Abstract: Hereditary hemolytic disorders are important public health challenges
in India. They cause a high degree of morbidity, mortality and fetal
wastage in vulnerable communities. Tradition-bound-psychosocial influences
are detrimental to the process of prevention. This study was designed
to create awareness, motivate, and sensitize two major vulnerable tribal
communities: Bhuyan and Kharia for hemoglobin and allied hemolytic disorders
in addition to imparting prospective and retrospective genetic/marriage
counseling. Bhuyan and Kharia tribal people in Orissa live in clusters
practicing inter-village tribal endogamy and clan exogamy. For the present
study, random sampling procedure for the selection of whole village
was followed. Imparting of education, motivation and sensitization for
carrier detection were carried out through IEC materials, holding interactive
meetings and discussions at district, block and village levels. Both
prospective and retrospective intervention and genetic/marriage counseling
was done through the local PHC doctor. The pre- and post-intervention
knowledge, attitude and practice (KAP) studies were conducted. Tribal
people were not knowing the signs and symptoms of sickle cell disease
(2.1%) and beta-thalassemia (1.0%), but after IEC, their knowledge was
considerably improved (67.8%, 56.4%, respectively). Sickle cell patient
needs treatment (37.6%) like folic acid, blood transfusion, etc. Beta-thalassemia
is disease causes bloodlessness and is a transfusion dependent (73.2%).
All patients of thalassemia major or sickle cell disease have carrier
parents and carriers do not suffer from any clinical ailments. After
intervention, it was known that G-6-PD is an enzyme, which helps in
glucose metabolism of red cells (76.4%) and its hereditary deficiency
causes hemolytic anemia, jaundice and black urination (73.8%) in malaria
cases when anti-malarials are administered. Methodical and prudent intervention
and preventive strategies found positive and encouraging impact on the
affected people. Success of strategy showed apparent overwhelming response
of the tribal people towards changing the traditional mindset and improving
their health and quality of life.
Key words: Hereditary
Hemolytic Disorders; Hemoglobinopathies; Sensitization and Motivation;
Carrier Detection; IEC/Intervention and Prevention; KAP Studies; Scheduled
Tribes |
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This Article |
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2010;3-5
Original Article |
Prakash M, Phani NM, Kavya R, Supriya M.
Urinary peptide levels in
patients with chronic renal failure. |
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Abstract: Introduction:
Peptide levels in urine are found to be decreased in renal failure.
In the current study urinary peptide levels were determined in chronic
renal failure (CRF) patients. Method: 86 CRF patients and 80
healthy controls were selected for the study. Urinary proteins and peptide
levels were determined by spectrophotometer based Lowry and Bradford
methods. Urinary creatinine levels were determined by clinical chemistry
analyzer. Results: There was significant decrease in urinary
peptide levels in CRF patients and Urinary % peptides were significantly
decreased in CRF patients as compared to healthy controls. Urinary %
peptides correlated negatively with proteinuria. Conclusion:
we have found decrease in urinary peptides and % urinary peptides in
CRF patients and possibly measurement of % urinary peptides may possibly serve
as better indicator in early detection of impairment in renal function.
Key words: Peptiduria; Proteinuria; Chronic renal failure; Urinary peptides |
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This Article |
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2010;3-6
Original Article |
Babu S, Shetty JK, Prakash M.
Total thiols
and MDA levels in Patients with Acute
Myocardial Infarction Before and After reperfusion therapy. |
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Background:
Reactive oxygen species have been implicated in the pathogenesis of
ischemic and reperfusion injury. In the current work we have measured
malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG
proven acute myocardial infarction (AMI) patients immediately after
admission and 24 hours after administration of thrombolytic agent streptokinase,
and in healthy controls. Methods:
Blood samples from 44 AMI patients and 25 age and sex matched healthy
controls were obtained and analyzed for MDA, total thiols using spectrophotometric
methods and cardiac enzymes CK, CK-MB and AST using automated analyzer. Results:
We have found significant increase in MDA, CPK, CK-MB, AST (p<
0.001) and significant decrease in total thiols (p<0.001) in AMI
patients after thrombolytic therapy compared to values at admission,
and healthy controls. MDA correlated negatively with total thiols (r
= - 0.333, p<0.05) and positively with CK-MB (r = 0.491, p<0.01)
in AMI patients after thrombolytic therapy. Conclusions:
Reperfusion following thrombolytic therapy increases reactive oxygen
species with concomitant decrease in antioxidant total thiols.
Key words: MDA; Total thiols; Myocardial infarction; Reperfusion injury
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This Article |
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2010;3-7
Original Article |
Hettihewa LM, Jayarathna
KAKT.
Comparison of the Knowledge in Core
Policies of Essential Drug List Among Medical Practitioners and Medical Students
in Galle, Sri Lanka. |
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Abstract: Selection of the best and safest medicine should be one of the national
economic policies in a country for good health care services. Introduction of
detailed module in rational use of medicine (RUM) to pharmacology syllabus
needed prior analysis of the existing knowledge among health care workers.
Therefore we assessed the knowledge and attitudes of essential drug list (EDL)
on medical practitioners (MPs) and medical students (MSs). Forty two MPs and 120
MSs from hospital and Faculty of Medicine were given a pretested structured
questionnaire related to core policies of EDL, contents, criteria for selection
and time frame for revision in RUM. Our study showed that only 29% of MPs were
confident about their knowledge in EDL and 17% of them had marked it as don’t
know. Study was expanded for quantitative analysis of the knowledge on the core
policies of EDL on them. Knowledge on contents, criteria for selection and the
time frame for revision of EDL were 63%, 83% and 17% in MPs. Of MSs, 87% had
sound knowledge in core contents, 32% in criteria for selection and only 50% of
MSs were aware about the correct time frame of revision of EDL. Knowledge in
contents of EDL was higher in MSs (87%) than MPs(63&). MPs were not aware
about EDL preparing criteria such as inclusion of generic names, common ailment,
majority ailments of the people (59%, 56% and 56% respectively). In contrast, MSs had > 93% of the knowledge in all three areas. However MSs had poorer
knowledge (32%) in criteria for selection of EDL than MPs (83%). Knowledge in
time frame for revision of EDL was 17% in MPs and 50% in MSs. We found that MPs
in the service were not convinced about their knowledge in EDL. Deficiency was
significant in the core contents of the EDL preparation. Therefore we suggest
that MPs need repetitive in-service training programme for practicing of RUM in
the national health facilities. We need to reiterative programme in the core curriculum regarding the criteria
for EDL selection. Though MSs had good knowledge in content of EDL, they are poor
in criteria for selection and time frame for revision
Key words: Rational
use of medicine; Essential drug list; Core policies; Medical practitioners;
Medical students |
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This Article |
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2010;3-8
Original Article |
Sabu KM, Nair NS, Sharma PSVN.
Development
of a Cost-Effective Database Software for Psychiatric Research: A Study From Tertiary Care Teaching Hospital. |
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Abstract: Background: Technological progression
made drastic changes in health care. Still there is a growing concern
about proper utilization of health information within hospitals for
various research activities. Huge volumes of such health information
in majority of hospitals are redundant due to lack of appropriate and
cost-effective technological tools for retrieving relevant health information
for research purpose. Objective: To develop a cost-effective
and user-friendly computerized medical record database for psychiatry
using available technology with the department.
Methodology: Study performed at a tertiary care teaching hospital
in Udupi district of South India. Various datasets from psychiatry medical
records were utilized for the design and creation of database. A computerized
database called PsyCase was developed with the help of technology available
within the department. A 4612 patient’s data were entered into the
PsyCase and subjected to various analyses. Results: Applications
of PsyCase in various epidemiological studies were explored through
performing numerous analyses with actual data. PsyCase was found effective
in supporting psychiatric research as well as routine clinical and administrative
activities. Conclusion: This study emphasizes need of appropriate
use of technology available within a healthcare system to facilitate
medical research in psychiatry and role of health information professional
in such initiatives. Healthcare organization must focus on collective
utilization of resources within the system to improve the utilization
of health information for medical research.
Key words: Cost-effective; Database; Epidemiology;
Medical records; Psychiatry |
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This Article |
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2010;3-9
Original Article |
Tantry TP, Vastrad NS, Koteshwar R, Prashanth Mohan, Kadri R, Kadam
D, Adappa K, Shenoy SP.
Butorphanol for Post-Operative Analgesia - A Comparative Clinical Study with Ketorolac. |
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Abstract: Introduction:
Butorphanol, an opioid derivative has been shown to have, in addition
to its analgesic properties, several other advantageous effects like
antistressor, sedative and anti-shivering action. The efficacy and safety
profile of ketorolac, yet another widely used post-operative analgesic
is well documented. This study aims to compare the two analgesics. Aims
and objectives: This study was conducted to compare the analgesic
efficacy and other effects of butorphanol and ketorolac, administered
intramuscularly, in post-operative patients who have undergone lower
abdominal surgeries. Materials
and methods: 50 patients undergoing lower abdominal and pelvic surgeries
under general or spinal anaesthesia were randomly divided into two Groups
(25 each). At a particular level of post-operative pain, the patients
Groups I and II were administered intramuscular ketorolac 30mg and butorphanol
2mg respectively. The analgesic effect was studied using Visual Analogue
Scale (VAS) and the verbal category scale. Patients were monitored for
the sedative action, respiratory status and other vital parameters for
300 minutes and for other adverse reactions over the next twelve hours. Observations:
Butorphanol provided better analgesia within the first two hours of
administration, while ketorolac was more effective at 4-5 hours. Better
sedative action without any significant respiratory depressant effect
was demonstrated with butorphanol. There were no clinically significant
hemodynamic fluctuations or adverse reactions with butorphanol or ketorolac. Conclusions:
Butorphanol provides better early analgesia as compared to ketorolac
with a desirable and safe sedative effect in post-operative patients
who have undergone lower abdominal and pelvic surgeries.
Key words: Acute post operative pain; Butorphanol; Ketorolac; Analgesia |
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This Article |
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2010;3-10
Original Article |
Alim F, Jahan F.
Impact of Prenatal
Checkups of Mothers and Immunization of Children on the Health Status of
Children (0- 3 years) - A Study in Rural Areas of Aligarh
District, Uttar Pradesh. |
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Abstract: Background
and objectives: A survey based study on rural areas
of Aligarh District was conducted to assess the prenatal checkups pregnant
women and its effects on health status of children between the age of
(0-3 years), and immunization received by children and its effects
on their health status. Methods:
Five hundred children from five villages of rural areas of Aligarh
District were randomly selected. For the purpose of the study, a self
prepared structured interview schedule was used. To get the qualitative
information of the study anthropometric measures include height weight
were used for assessing growth pattern of the child. The stepwise analysis
of two variables height for age and weight for age was done on the basis
of Water low’s and Gomez’ classification. To examine the relationship
between Health Status of the child and selected variable that affects
Health Status of children, Chi-square test was employed. Results:
Based on Gomez’ classification out of 88% mothers who did not go for
prenatal ups majority 80% of children were underweight, and 80% of children
who did not receive immunization majority 60% were underweight. Based
on Waterlow’s classification majority 68% of children were stunted
whose mother did not go for prenatal checkups and 50% of their children
were stunted who did not receive immunization. Conclusion:
Majority of children were stunted whose mother did not go for prenatal
checkup and the children who did not receive immunization.
Key words: Prenatal checkups; Stunted growth; Underweight; Immunization |
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This Article |
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2010;3-11
Original Article |
Latha KS, Annapoorna K.
Profile of Clients seeking Consultation
at Yoga Therapy Department: A Cross sectional Study Oncogenic Potential
of Radiofrequecy Emissions for Mobile Phones. |
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Abstract: It is estimated that between 10% and
30% of the general practice population are mentally or emotionally disturbed.
Physical complaints, multiple aches and pains are construed
as signs and symptoms of stress. Although yoga is considered as beneficial, any
hidden psychiatric morbidity may go undetected and thus untreated. Thus
the aim of this study was to obtain an estimate of hidden psychiatric
morbidity in clients seeking consultation at
the Department of Yoga. Fifty respondents
were administered Life Satisfaction Scale and General Health Questionnaire-12.
Majority were females, younger, graduates, married and also scored
above the cut off on GHQ, suggesting minor psychiatric disorder/distress;
reasons for consultation were related to being over weight, stress, aches and
pains, poor concentration. A significant number of persons reported of some
dissatisfaction in life. The perceived benefits were related to reducing
symptoms, stress, weight, relaxation and improvement in concentration and
memory.
Key words: Yoga; Minor psychiatric
disorders; Stress; Tension; Relaxation; GHQ-12 |
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This Article |
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2010;3-12
Original Article |
Sinha T, Tiwari S.
DOTS Compliance by Tuberculosis Patients in District Raipur (Chhattisgarh). |
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Abstract: Background:
Compliance to therapy is one of the important factors that affect the
outcome. Non-compliance
to self administered multi drug tuberculosis treatment regimens is an important cause of failure of initial therapy and relapse
as well as acquired drug resistance, requiring
more prolonged and expensive therapy. Objective: To know the compliance of DOTS therapy in TB patients in District
Raipur and to find out the reasons of non-compliance of DOTS therapy
among the patients. Study Design: Cross sectional observational
community based study. Study Setting: Microscopic Centers in District Raipur. Participants: 695 patients of Tuberculosis. Result:
Study revealed that 65.93% patients had complied with the DOTS therapy and
33.38% were non compliant. Conclusion:
Most of the reasons of non-Compliance can be averted by proper counseling
of target group. Hence to achieve the goal of RNTCP, proper counseling
of target group must be given top priority.
Key words: Counseling; DOTS; Non compliance |
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This Article |
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2010;3-13
Original Article |
Shankar G, Yogita.
Effectiveness
of passive stretching versus hold relax technique in flexibility of
hamstring muscle. |
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Withdrawn due to
dual publication by authors |
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Withdrawn |
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2010;3-14
Original Article |
Biswas D, Roy S, Lenka PK, Kumar R.
Energy
Cost and Gait Efficiency of Below-Knee Amputee and Normal Subject
with Similar Physical Parameters & Quality of Life: A Comparative
Case Study. |
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Abstract: The
study focused on the comparative analysis of energy cost and gait efficiency
between a below knee (BK) amputee and a reference subject (without amputation).
It also attempted to indicate the specific feature responsible for a
controlled gait with optimum energy cost for BK amputees. Selection
criteria of the subjects were similar physical parameters and quality
of life studied with WHOQOL-100
quality of life assessment. A Cosmed® k4 b2 Respiratory
Analyzer system was used for the measurement of Oxygen Uptake (VO2),
Energy Expenditure per minute (EE) and Heart Rate (HR). Gait efficiency
(p <0.0002) was found higher for BK amputee than normal subject.
The therapeutic activities and mainly walking rhythm contributed to
improve the mobility & balance. This ensures the optimum time &
co-ordination of movements and hence improves the gait efficiency for
the BK amputee. Comparison with control group was performed to validate the data.
Key words: Energy Cost; Gait Efficiency; Below knee amputee |
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This Article |
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2010;3-15
Short Report |
Patil P, Hulke S, Thakre A, Gaikwad M.
Pen of Health
Care Worker as Vector of Infection. |
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Abstract: Nosocomial
infections are the major concern in tertiary hospitals. Health care
workers and their belonging are known to act as vector in transmission
of infections. In present study, the writing pen of health care workers
was worked out for carrying infection. The swab from writing pen of
health care workers were cultured for any growth of microorganism and
compared with swab from pen of the non health care workers. It was found
that the rate of growth of microorganism were more in pen of health
care workers. Similarly the organism attributed to the nosocomial infection
was grown from the pens of health care workers. These organisms might
be transmitted from the hands of health care workers. The writing pen
which health care worker are using became the vectors of transmission
of infection. So to prevent it, the most important way is to wash the
hands and pen properly after examining the patients.
Key words: Pen; Vector; Microorganism; Health care worker; Nosocomial infection |
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This Article |
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2010;3-16
Short Report |
Aidonis
I, Skalimis A, Kyrodimos E.
Persistent Hiccups Following
Stapedectomy. |
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Abstract: Objective:
We report a case of a 37 year-old man who developed persistent hiccups
after elective stapedectomy. Method and
Results: The diagnostic approach is discussed as well as the non-pharmacologic
and pharmacologic treatments and overall management. The aim is to stress
that there is a variety of potential factors that can induce hiccups
perioperatively and in cases like this a step by step approach must
be taken. Conclusion:
Persistent hiccups are very rare following stapedectomy, control of
them is crucial for the successful outcome. The trigger may be more
than one factors and the good response to treatment may be due to dealing
successfully with more than one thing.
Key words: Intractable; Singultus; Stapedectomy; Postoperative hiccups |
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This Article |
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2010;3-17
Case Report |
Abhishek MG, Vijayshankar S, Krishnappa A.
Pitfalls
in Cytodiagnosis of Pleomorphic Adenoma of the Nasal Septum - A
Rare Case Report. |
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Abstract: Pleomorphic
adenoma is the most common benign mixed tumor of major salivary gland.
Ectopic occurrence of pleomorphic adenoma are seen in minor salivary
glands of pharynx, trachea, larynx and very rarely in nasal septum.
We report a case of 40 year old female who presented with right sided
nasal mass and mild nasal obstruction since six months. Cytologically
a possibility of pleomorphic adenoma was made which was confirmed by
histopathological study. We present this case due to 1) rarity in the
nasal septum 2) pitfalls at cytology due to abundance (predominance)
of myoepithelial cells and scanty or even absent mesenchymal component
and 3) under reporting in English literature to the best of our knowledge.
Key words: Pleomorphic adenoma; Nasal septum; Fine needle aspiration cytology |
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This Article |
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2010;3-18
Case Report |
Geethalakshmi U, Vijayshankar S,
Abhishek MG, Indira CS.
Primary Cutaneous Low
Grade Mucinous Adenocarcinoma of Eyelid. |
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Abstract: Primary cutaneous mucinous adenocarcinoma is a rare adnexal neoplasm,
eyelid being the most common site of presentation. Clinically it is
mistaken for a benign / cystic lesion. Its morphologic similarity to
metastatic deposits from breast, gastrointestinal tract (GIT) or any
visceral sites adds to the diagnostic difficulty mandating the role
of ancillary techniques in precise diagnosis and hence planning the
management. We report a
case of primary cutaneous mucinous adenocarcinoma of eyelid with emphasis
on pathology along with a brief review of literature.
Key words: Mucinous adenocarcinoma; Eyelid; Immunohistochemistry |
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This Article |
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2010;3-19
Case Report |
Shetty PK, Balaiah K, Bafna UD.
Uterine Papillary Serous Carcinoma with Mature Cystic
Teratoma of Left Ovary. |
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Abstract: Uterine
papillary serous carcinoma (UPSC) is an uncommon histologic variant of
endometrial carcinoma that typically arises in post menopausal women, that may present with extrauterine
spread, resulting in high relapse rate and poor prognosis. Mature cystic
teratomas (MCT) are common tumors that occur during the reproductive years. We report a case of
a 60 years old female with UPSC with MCT of left ovary. To
our knowledge, this is the second report of UPSC combined with ovarian
MCT.
Key words: Uterine papillary serous carcinoma (UPSC); Mature cystic teratoma; CA 125 |
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This Article |
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2010;3-20
Case Report |
Vijayshankar S, Amita K,
Abhishek M, Manjunath D.
Sporadic Medullary Microcarcinoma in a Young Patient - A Rare Case. |
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Abstract: Sporadic medullary
microcarcinoma of thyroid is a rare disease detected usually in 0.15%
of all thyroid malignancy. We report a case of sporadic medullary microcarcinoma
(MMC) of thyroid in a 24 year old male presenting as solitary thyroid
nodule. There was no family history of medullary carcinoma of thyroid.
Although medullary carcinoma in a familial setting have been reported,
sporadic MMC is rare especially in a young patient.
Key words: Medullary microcarcinoma; Sporadic; Solitary thyroid nodule |
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This Article |
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2010;3-21
Case Report |
Shetty PK, Baliga SV, Balaiah K, Gnana Prakash S.
Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry
in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as
obscure gastrointestinal haemorrhage. |
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Abstract: Gastrointestinal stromal tumors (GIST) are relatively rare tumors of
gastrointestinal (GI) tract, most commonly arise from the stomach followed
by small intestine and colon, clinically GIST present with occult GI
bleeding, abdominal pain and intestinal obstruction. We present a case
of a jejunal GIST, which presented as an obscure GI haemorrhage. This
case highlights how oesophagogastrodudenectomy and colonoscopy proved
inconclusive in determining source of bleeding and the importance of
RBC labeled 99m-Tc scan in detecting the source of GI bleeding
and also emphasizes on histopathology and immunohistochemistry in diagnosis
of GIST.
Key words: Gastrointestinal
stromal tumor; RBC labeled 99m-Tc scan; Immunohistochemistry |
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This Article |
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2010;3-22
Case Report |
Vijayshankar S, Usha R, Rao V, Siddappa S.
Amoeboma-
An Interesting Case Report With an Unusual Presentation. |
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Abstract: Amebiasis is an infectious disease caused by Entamoeba Histolytica
is more common in devolping countries, with various clinical manifestations
and sequalae. Amoeboma , is an unusual sequelae which manifests as a
tumor like mass within the colon. We present an unusual case of 5 year
old child with signs of acute abdomen. A mass was found on expoloratory
laparotomy attached to the small intestine. Histopathological examination
of the mass revealed numerous amoebic trophozoites and the diagnosis
of amoeboma was made. Our case is unusual because amoebomas presenting
as an extraluminal mass attached to small intestine is extremely uncommon.
Key words: Amoeboma;
Small intestine; Extraluminal mass |
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